The apparently unstoppable rise of e-commerce is contributing to radically alter the urban landscape, with a major impact on the traditional retail sector and important consequences on new forms of logistics and organization.

At the same time, the control of e-commerce platforms is strongly connected to market power issues, since this sector is considered to be one of the most critical infrastructures for the future trajectories of goods and services production and consumption.

In this context, regulators should pay particular attention to a series of problems, such as the pricing practices adopted by e-commerce platforms, the relationship between the concentration in few hands of big data on customers' behavior and possible harms to competition, potential issues of discrimination  between suppliers that use the platform essential facility as a digital channel and, finally, unfair competition on product quality and variety brought about by the use of data that are only available for the platform.